METHADONE PROGRAM FUNDAMENTALS EXPLAINED

CYP2B6 is An important CYP enzyme linked to the metabolism of S-methadone and to an extent, R-methadone. The expression of CYP2B6The metabolism and elimination of methadone and buprenorphine could be affected by both hepatic or renal dysfunction in which case the dose or dosing frequency should be altered appropriately.Methadone maintenance treatme